Wireless on-demand drug delivery

Biological lipid membranes for on-demand, wireless drug delivery from thin, bioresorbable electronic implants

On-demand, localized release of drugs in precisely controlled, patient-specific time sequences represents an ideal scenario for pharmacological treatment of various forms of hormone imbalances, malignant cancers, osteoporosis, diabetic conditions and others. We present a wirelessly operated, implantable drug delivery system that offers such capabilities in a form that undergoes complete bioreso...

A low power, on demand electrothermal valve for wireless drug delivery applications.

We present a low power, on demand Parylene MEMS electrothermal valve. A novel Omega-shaped thermal resistive element requires low power (approximately mW) and enables rapid valve opening (approximately ms). Using both finite element analysis and valve opening experiments, a robust resistive element design for improved valve opening performance in water was obtained. In addition, a thermistor, a...

Active scaffolds for on-demand drug and cell delivery.

Porous biomaterials have been widely used as scaffolds in tissue engineering and cell-based therapies. The release of biological agents from conventional porous scaffolds is typically governed by molecular diffusion, material degradation, and cell migration, which do not allow for dynamic external regulation. We present a new active porous scaffold that can be remotely controlled by a magnetic ...

Drug Delivery Approaches with Special Emphasis on Chemical Drug Delivery

MessageBox: An On-Demand Message Delivery Service

We propose a new message delivery service called MessageBox. The service allows the writer of the message to provide on-demand message delivery using email to a list of readers. The writer specifies the list of authorized readers; such readers may request email delivery of the message at their convenience. Simple security mechanisms thwart unauthorized readers. We describe three applications of...